PMS1 Antikörper (AA 441-490)

Produktnummer ABIN1534483

Der Kaninchen Polyklonal anti-PMS1 Antikörper wird verwendet zum Nachweis von PMS1 in Proben von Human, Ratte und Maus. Er wurde validiert für WB, ELISA, IHC und IF.

Kurzübersicht für PMS1 Antikörper (AA 441-490) (ABIN1534483)

Target: PMS1 (PMS1 Postmeiotic Segregation Increased 1 (S. Cerevisiae) (PMS1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PMS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-PMS1 Antikörper

Bindungsspezifität: AA 441-490

Verwendungszweck: PMS1 Antibody

Spezifität: PMS1 Polyclonal Antibody detects endogenous levels of PMS1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human PMS1. AA range:441-490

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu PMS1

Target: PMS1 (PMS1 Postmeiotic Segregation Increased 1 (S. Cerevisiae) (PMS1))

Andere Bezeichnung: PMS1

Hintergrund:

Synonyms: PMS1, PMSL1, PMS1 protein homolog 1, DNA mismatch repair protein PMS1

Background: This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome. [provided by RefSeq, Jul 2008],

Gene Name: PMS1

Protein Name: PMS1 protein homolog 1

Molekulargewicht: 105 kDa

Gen-ID: 5378

OMIM: 600258

UniProt: P54277