PMS1 Antikörper (AA 410-490)

Produktnummer ABIN7216618

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PMS1 in WB, ELISA, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für PMS1 Antikörper (AA 410-490) (ABIN7216618)

Target: PMS1 (PMS1 Postmeiotic Segregation Increased 1 (S. Cerevisiae) (PMS1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PMS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-PMS1 Antikörper

Bindungsspezifität: AA 410-490

Verwendungszweck: Rabbit Anti-PMS1 Polyclonal Antibody

Spezifität: PMS1 Polyclonal Antibody detects endogenous levels of PMS1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human PMS1 at AA range: 410-490

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu PMS1

Target: PMS1 (PMS1 Postmeiotic Segregation Increased 1 (S. Cerevisiae) (PMS1))

Andere Bezeichnung: PMS1

Hintergrund: PMS1, PMSL1, PMS1 protein homolog 1, DNA mismatch repair protein PMS1PMS1 encodes a protein belonging to the DNA mismatch repair mutL/hexB family. PMS1 homolog 1, mismatch repair system component is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in PMS1 cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.

Molekulargewicht: 105kD

Gen-ID: 5378

UniProt: P54277