CENPA Antikörper (AA 11-60)

Produktnummer ABIN1534330

Der Kaninchen Polyklonal anti-CENPA Antikörper wird verwendet zum Nachweis von CENPA in Proben von Human, Ratte und Maus. Er wurde validiert für ELISA, IHC und IF.

Kurzübersicht für CENPA Antikörper (AA 11-60) (ABIN1534330)

Target: CENPA (Centromere Protein A (CENPA))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CENPA Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-CENPA Antikörper

Bindungsspezifität: AA 11-60

Verwendungszweck: CENP-A Antibody

Spezifität: CENP-A Polyclonal Antibody detects endogenous levels of CENP-A protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CENPA. AA range:11-60

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu CENPA

Target: CENPA (Centromere Protein A (CENPA))

Andere Bezeichnung: CENPA

Hintergrund:

Synonyms: CENPA, Histone H3-like centromeric protein A, Centromere autoantigen A, Centromere protein A, CENP-A

Background: Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes.This gene encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. The protein is a replication-independent histone that is a member of the histone H3 family. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2015],

Gene Name: CENPA

Protein Name: Histone H3-like centromeric protein A

Molekulargewicht: 15 kDa

Gen-ID: 1058

OMIM: 117139

UniProt: P49450

Pathways: Chromatin Binding, Maintenance of Protein Location