ERAP1 Antikörper (AA 441-490)

Produktnummer ABIN1534157

Der Kaninchen Polyklonal anti-ERAP1 Antikörper (ABIN1534157) detektiert spezifisch ERAP1 in WB, ELISA, IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für ERAP1 Antikörper (AA 441-490) (ABIN1534157)

Target: ERAP1 (Endoplasmic Reticulum Aminopeptidase 1 (ERAP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-ERAP1 Antikörper

Bindungsspezifität: AA 441-490

Verwendungszweck: ERAP1 Antibody

Spezifität: ERAP1 Polyclonal Antibody detects endogenous levels of ERAP1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ARTS-1. AA range:441-490

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu ERAP1

Target: ERAP1 (Endoplasmic Reticulum Aminopeptidase 1 (ERAP1))

Andere Bezeichnung: ARTS-1

Hintergrund:

Synonyms: ERAP1, APPILS, ARTS1, KIAA0525, Endoplasmic reticulum aminopeptidase 1, ARTS-1, Adipocyte-derived leucine aminopeptidase, A-LAP, Aminopeptidase PILS, Puromycin-insensitive leucyl-specific aminopeptidase, PILS-AP, Type 1 tumor necrosis facto

Background: The protein encoded by this gene is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for this gene.[provided by RefSeq, Oct 2010],

Gene Name: ERAP1

Protein Name: Endoplasmic reticulum aminopeptidase 1

Molekulargewicht: 107 kDa

Gen-ID: 51752

OMIM: 606832

UniProt: Q9NZ08