ARNT2 Antikörper (AA 21-70)

Produktnummer ABIN1534136

Der Kaninchen Polyklonal anti-ARNT2 Antikörper (ABIN1534136) detektiert spezifisch ARNT2 in WB, ELISA, IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für ARNT2 Antikörper (AA 21-70) (ABIN1534136)

Target: ARNT2 (Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARNT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-ARNT2 Antikörper

Bindungsspezifität: AA 21-70

Verwendungszweck: Arnt 2 Antibody

Spezifität: Arnt 2 Polyclonal Antibody detects endogenous levels of Arnt 2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ARNT2. AA range:21-70

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu ARNT2

Target: ARNT2 (Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2))

Andere Bezeichnung: ARNT2

Hintergrund:

Synonyms: ARNT2, BHLHE1, KIAA0307, Aryl hydrocarbon receptor nuclear translocator 2, ARNT protein 2, Class E basic helix-loop-helix protein 1, bHLHe1

Background: aryl hydrocarbon receptor nuclear translocator 2(ARNT2) Homo sapiens This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting additional roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively. [provided by RefSeq, Dec 2013],

Gene Name: ARNT2

Protein Name: Aryl hydrocarbon receptor nuclear translocator 2

Molekulargewicht: 78 kDa

Gen-ID: 9915

OMIM: 606036

UniProt: Q9HBZ2

Pathways: Warburg Effekt