STRADA Antikörper (AA 11-60)

Produktnummer ABIN1533974

Der Kaninchen Polyklonal anti-STRADA Antikörper (ABIN1533974) detektiert spezifisch STRADA in WB, ELISA, IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für STRADA Antikörper (AA 11-60) (ABIN1533974)

Target: STRADA (STE20-Related Kinase Adaptor alpha (STRADA))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STRADA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-STRADA Antikörper

Bindungsspezifität: AA 11-60

Verwendungszweck: Strad Antibody

Spezifität: Strad Polyclonal Antibody detects endogenous levels of Strad protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human STRAD. AA range:11-60

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu STRADA

Target: STRADA (STE20-Related Kinase Adaptor alpha (STRADA))

Andere Bezeichnung: STRAD

Hintergrund:

Synonyms: STRADA; LYK5; STRAD; STE20-related kinase adapter protein alpha; STRAD alpha; STE20-related adapter protein; Serologically defined breast cancer antigen NY-BR-96

Background: The protein encoded by this gene contains a STE20-like kinase domain, but lacks several residues that are critical for catalytic activity, so it is termed a ' pseudokinase' . The protein forms a heterotrimeric complex with serine/threonine kinase 11 (STK11, also known as LKB1) and the scaffolding protein calcium binding protein 39 (CAB39, also known as MO25). The protein activates STK11 leading to the phosphorylation of both proteins and excluding STK11 from the nucleus. The protein is necessary for STK11-induced G1 cell cycle arrest. A mutation in this gene has been shown to result in polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their full-length nature is not known. [provided by RefSeq, Sep 2009],

Gene Name: STRADA

Protein Name: STE20-related kinase adapter protein alpha

Molekulargewicht: 48 kDa

Gen-ID: 92335

OMIM: 608626

UniProt: Q7RTN6

Pathways: AMPK Signaling