UNG Antikörper (AA 191-240)
Kurzübersicht für UNG Antikörper (AA 191-240) (ABIN1533614)
Target
Alle UNG Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 191-240
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Verwendungszweck
- UDG Antibody
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Spezifität
- UDG Polyclonal Antibody detects endogenous levels of UDG protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human UNG. AA range:191-240
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- UNG (Uracil-DNA Glycosylase (UNG))
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Andere Bezeichnung
- UNG
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Hintergrund
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Synonyms: UNG, DGU, UNG1, UNG15, Uracil-DNA glycosylase, UDG
Background: This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. [provided by RefSeq, Nov 2010],
Gene Name: UNG
Protein Name: Uracil-DNA glycosylase
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Molekulargewicht
- 34 kDa
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Gen-ID
- 7374
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OMIM
- 191525
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UniProt
- P13051
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Pathways
- DNA Reparatur, Production of Molecular Mediator of Immune Response
Target
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