NDC80 Antikörper (AA 351-400)

Produktnummer ABIN1533486

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch NDC80 in WB, ELISA und IF. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für NDC80 Antikörper (AA 351-400) (ABIN1533486)

Target: NDC80 (NDC80 Kinetochore Complex Component Homolog (NDC80))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NDC80 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-NDC80 Antikörper

Bindungsspezifität: AA 351-400

Verwendungszweck: Hec1 Antibody

Spezifität: Hec1 Polyclonal Antibody detects endogenous levels of Hec1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human KNTC2. AA range:351-400

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu NDC80

Target: NDC80 (NDC80 Kinetochore Complex Component Homolog (NDC80))

Andere Bezeichnung: KNTC2

Hintergrund:

Synonyms: NDC80, HEC, HEC1, KNTC2, Kinetochore protein NDC80 homolog, Highly expressed in cancer protein, Kinetochore protein Hec1, HsHec1, Kinetochore-associated protein 2, Retinoblastoma-associated protein HEC

Background: This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation. [provided by RefSeq, Oct 2011],

Gene Name: NDC80

Protein Name: Kinetochore protein NDC80 homolog

Molekulargewicht: 73 kDa

Gen-ID: 10403

OMIM: 607272

UniProt: O14777

Pathways: Maintenance of Protein Location