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NDC80 Antikörper (C-Term)

NDC80 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6263548
  • Target Alle NDC80 Antikörper anzeigen
    NDC80 (NDC80 Kinetochore Complex Component Homolog (NDC80))
    Bindungsspezifität
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 45
    • 20
    • 11
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 39
    • 6
    • 1
    Kaninchen
    Klonalität
    • 41
    • 5
    Polyklonal
    Konjugat
    • 29
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser NDC80 Antikörper ist unkonjugiert
    Applikation
    • 26
    • 17
    • 10
    • 7
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    NDC80 Antibody detects endogenous levels of total NDC80.
    Homologie
    Dog
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human NDC80, corresponding to a region within C-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product NDC80 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    NDC80 (NDC80 Kinetochore Complex Component Homolog (NDC80))
    Andere Bezeichnung
    NDC80 (NDC80 Produkte)
    Synonyme
    CG9938 antikoerper, Dmel\\CG9938 antikoerper, Hec1 antikoerper, NDC80 antikoerper, dNdc80 antikoerper, dmNdc80 antikoerper, hec1 antikoerper, KNTC2 antikoerper, ndc10 antikoerper, tid3 antikoerper, 2610020P18Rik antikoerper, AV139730 antikoerper, HEC antikoerper, HEC1 antikoerper, Kntc2 antikoerper, kntc2l antikoerper, wu:fb52e02 antikoerper, zgc:111801 antikoerper, HsHec1 antikoerper, TID3 antikoerper, hsNDC80 antikoerper, kntc2 antikoerper, NDC80, kinetochore complex component antikoerper, CG9938 gene product from transcript CG9938-RA antikoerper, spindle pole body protein Ndc80 antikoerper, kinetochore protein Ndc80 antikoerper, NDC80 homolog, kinetochore complex component (S. cerevisiae) antikoerper, NDC80 kinetochore complex component antikoerper, NDC80 kinetochore complex component S homeolog antikoerper, NDC80 antikoerper, Ndc80 antikoerper, ndc80 antikoerper, ndc80.S antikoerper
    Hintergrund

    Description: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:9315664, PubMed:12351790, PubMed:14654001, PubMed:14699129, PubMed:15062103, PubMed:15235793, PubMed:15239953, PubMed:15548592, PubMed:16732327). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore (PubMed:15548592). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules (PubMed:23085020). Plays a role in chromosome congression and is essential for the end-on attachment of the kinetochores to spindle microtubules (PubMed:25743205, PubMed:23891108).

    Gene: NDC80

    Molekulargewicht
    74kDa
    Gen-ID
    10403
    UniProt
    O14777
    Pathways
    Maintenance of Protein Location
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