RCC1 Antikörper (AA 517-566)

Produktnummer ABIN1533464

Der Kaninchen Polyklonal anti-RCC1 Antikörper (ABIN1533464) detektiert spezifisch RCC1 in WB, IHC, IF und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für RCC1 Antikörper (AA 517-566) (ABIN1533464)

Target: RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RCC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Produktdetails anti-RCC1 Antikörper

Bindungsspezifität: AA 517-566

Verwendungszweck: XRCC1 Antibody

Spezifität: XRCC1 Polyclonal Antibody detects endogenous levels of XRCC1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human XRCC1. AA range:517-566

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu RCC1

Target: RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

Andere Bezeichnung: RCC1

Hintergrund:

Synonyms: XRCC1, DNA repair protein XRCC1, X-ray repair cross-complementing protein 1

Background: The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008],

Gene Name: XRCC1

Protein Name: DNA repair protein XRCC1

Molekulargewicht: 69 kDa

Gen-ID: 7515

OMIM: 194360

UniProt: P18887

Pathways: Chromatin Binding, Protein targeting to Nucleus