PAX5 Antikörper (AA 1-50)
Kurzübersicht für PAX5 Antikörper (AA 1-50) (ABIN1533375)
Target
Alle PAX5 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-50
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Verwendungszweck
- Pax-5 Antibody
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Spezifität
- Pax-5 Polyclonal Antibody detects endogenous levels of Pax-5 protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human Pax-5. AA range:1-50
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- PAX5 (Paired Box 5 (PAX5))
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Andere Bezeichnung
- Pax-5
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Hintergrund
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Synonyms: PAX5, Paired box protein Pax-5, B-cell-specific transcription factor, BSAP
Background: This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. Paired box transcription factors are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation.This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9,14)(p13,q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer
Gene Name: PAX5
Protein Name: Paired box protein Pax-5
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Molekulargewicht
- 42 kDa
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Gen-ID
- 5079
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OMIM
- 167414
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UniProt
- Q02548
Target
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