Dysferlin Antikörper (AA 1981-2030)

Produktnummer ABIN1533258

Der Kaninchen Polyklonal anti-Dysferlin Antikörper wird verwendet zum Nachweis von Dysferlin in Proben von Human und Maus. Er wurde validiert für WB, ELISA und IF.

Kurzübersicht für Dysferlin Antikörper (AA 1981-2030) (ABIN1533258)

Target: Dysferlin (DYSF)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dysferlin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-Dysferlin Antikörper

Bindungsspezifität: AA 1981-2030

Verwendungszweck: Dysferlin Antibody

Spezifität: Dysferlin Polyclonal Antibody detects endogenous levels of Dysferlin protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Dysferlin. AA range:1981-2030

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu Dysferlin

Target: Dysferlin (DYSF)

Andere Bezeichnung: Dysferlin

Hintergrund:

Synonyms: DYSF, FER1L1, Dysferlin, Dystrophy-associated fer-1-like protein, Fer-1-like protein 1

Background: dysferlin(DYSF) Homo sapiens The protein encoded by this gene belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. In addition,The protein encoded by this gene binds caveolin-3, a skeletal muscle membrane protein which is important in the formation of caveolae. Specific mutations in this gene have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2008],

Gene Name: DYSF

Protein Name: Dysferlin

Molekulargewicht: 237 kDa

Gen-ID: 8291

OMIM: 253601

UniProt: O75923