CLDN10 Antikörper (AA 179-228)

Produktnummer ABIN1533233

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CLDN10 in ELISA, WB, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für CLDN10 Antikörper (AA 179-228) (ABIN1533233)

Target: CLDN10 (Claudin 10 (CLDN10))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLDN10 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-CLDN10 Antikörper

Bindungsspezifität: AA 179-228

Verwendungszweck: Claudin-10 Antibody

Spezifität: Claudin-10 Polyclonal Antibody detects endogenous levels of Claudin-10 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Claudin 10. AA range:179-228

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu CLDN10

Target: CLDN10 (Claudin 10 (CLDN10))

Andere Bezeichnung: Claudin 10

Hintergrund:

Synonyms: CLDN10, Claudin-10, OSP-like protein

Background: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The expression level of this gene is associated with recurrence of primary hepatocellular carcinoma. Six alternatively spliced transcript variants encoding different isoforms have been reported, but the transcript sequences of some variants are not determined.[provided by RefSeq, Jun 2010],

Gene Name: CLDN10

Protein Name: Claudin-10

Molekulargewicht: 24 kDa

Gen-ID: 9071

UniProt: P78369

Pathways: Hepatitis C