CLDN10 Antikörper (AA 150-230)

Produktnummer ABIN7225798

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CLDN10 in ELISA, WB, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für CLDN10 Antikörper (AA 150-230) (ABIN7225798)

Target: CLDN10 (Claudin 10 (CLDN10))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLDN10 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-CLDN10 Antikörper

Bindungsspezifität: AA 150-230

Verwendungszweck: Rabbit Anti-Claudin-10 Polyclonal Antibody

Spezifität: Claudin-10 Polyclonal Antibody detects endogenous levels of Claudin-10 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human Claudin-10 at AA range: 150-230

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu CLDN10

Target: CLDN10 (Claudin 10 (CLDN10))

Andere Bezeichnung: Claudin-10

Hintergrund: CLDN10, Claudin-10, OSP-like proteinCLDN10 (claudin 10) encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The expression level of CLDN10 is associated with recurrence of primary hepatocellular carcinoma. Six alternatively spliced transcript variants encoding different isoforms have been reported, but the transcript sequences of some variants are not determined.

Molekulargewicht: 25kD

Gen-ID: 9071

UniProt: P78369

Pathways: Hepatitis C