SP1 Antikörper (AA 706-755)

Produktnummer ABIN1533004

Der Kaninchen Polyklonal anti-SP1 Antikörper wird verwendet zum Nachweis von SP1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, IHC, IF und ELISA.

Kurzübersicht für SP1 Antikörper (AA 706-755) (ABIN1533004)

Target: SP1 (Sp1 Transcription Factor (SP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Produktdetails anti-SP1 Antikörper

Bindungsspezifität: AA 706-755

Verwendungszweck: Sp1 Antibody

Spezifität: Sp1 Polyclonal Antibody detects endogenous levels of Sp1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human SP1. AA range:706-755

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu SP1

Target: SP1 (Sp1 Transcription Factor (SP1))

Andere Bezeichnung: SP1

Hintergrund:

Synonyms: SP1, TSFP1, Transcription factor Sp1

Background: The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014],

Gene Name: SP1

Protein Name: Transcription factor Sp1

Molekulargewicht: 80 kDa

Gen-ID: 6667

OMIM: 189906

UniProt: P08047

Pathways: Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction