WASF1 Antikörper (AA 91-140)

Produktnummer ABIN483044

Der Kaninchen Polyklonal anti-WASF1 Antikörper wird verwendet zum Nachweis von WASF1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, IHC, ELISA und IF.

Kurzübersicht für WASF1 Antikörper (AA 91-140) (ABIN483044)

Target: WASF1 (WAS Protein Family, Member 1 (WASF1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WASF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-WASF1 Antikörper

Bindungsspezifität: AA 91-140

Verwendungszweck: WAVE1 Antibody

Spezifität: WAVE1 Polyclonal Antibody detects endogenous levels of WAVE1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human WAVE1. AA range:91-140

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu WASF1

Target: WASF1 (WAS Protein Family, Member 1 (WASF1))

Andere Bezeichnung: WAVE1

Hintergrund:

Synonyms: WASF1, KIAA0269, SCAR1, WAVE1, Wiskott-Aldrich syndrome protein family member 1, WASP family protein member 1, Protein WAVE-1, Verprolin homology domain-containing protein 1

Background: The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],

Gene Name: WASF1

Protein Name: Wiskott-Aldrich syndrome protein family member 1

Molekulargewicht: 61 kDa

Gen-ID: 8936

OMIM: 605035

UniProt: Q92558

Pathways: RTK Signalweg, Regulation of Actin Filament Polymerization