NKX2-1 Antikörper (AA 79-128)

Produktnummer ABIN1532418

Der Kaninchen Polyklonal anti-NKX2-1 Antikörper wird verwendet zum Nachweis von NKX2-1 in Proben von Human, Maus und Ratte. Er wurde validiert für IHC, WB, IF und ELISA.

Kurzübersicht für NKX2-1 Antikörper (AA 79-128) (ABIN1532418)

Target: NKX2-1 (NK2 Homeobox 1 (NKX2-1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NKX2-1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), ELISA

Produktdetails anti-NKX2-1 Antikörper

Bindungsspezifität: AA 79-128

Verwendungszweck: p23 Antibody

Spezifität: P23 Polyclonal Antibody detects endogenous levels of p23 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human TEBP. AA range:79-128

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu NKX2-1

Target: NKX2-1 (NK2 Homeobox 1 (NKX2-1))

Andere Bezeichnung: TEBP

Hintergrund:

Synonyms: PTGES3, P23, TEBP, Prostaglandin E synthase 3, Cytosolic prostaglandin E2 synthase, cPGES, Hsp90 co-chaperone, Progesterone receptor complex p23, Telomerase-binding protein p23

Background: This gene encodes an enzyme that converts prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). This protein functions as a co-chaperone with heat shock protein 90 (HSP90), localizing to response elements in DNA and disrupting transcriptional activation complexes. Alternative splicing results in multiple transcript variants. There are multiple pseudogenes of this gene on several different chromosomes. [provided by RefSeq, Feb 2016],

Gene Name: PTGES3

Protein Name: Prostaglandin E synthase 3

Molekulargewicht: 18 kDa

Gen-ID: 10728

OMIM: 607061

UniProt: Q15185

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Glucan Metabolic Process, Feeding Behaviour