RHOA Antikörper (AA 144-193)

Produktnummer ABIN1532406

Der Kaninchen Polyklonal anti-RHOA Antikörper wird verwendet zum Nachweis von RHOA in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IHC und IF.

Kurzübersicht für RHOA Antikörper (AA 144-193) (ABIN1532406)

Target: RHOA (Ras Homolog Gene Family, Member A (RHOA))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RHOA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-RHOA Antikörper

Bindungsspezifität: AA 144-193

Verwendungszweck: Rho A Antibody

Spezifität: Rho A Polyclonal Antibody detects endogenous levels of Rho A protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human RhoA. AA range:144-193

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF 1:50-200 WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu RHOA

Target: RHOA (Ras Homolog Gene Family, Member A (RHOA))

Andere Bezeichnung: RhoA

Hintergrund:

Synonyms: RHOA, ARH12, ARHA, RHO12, Transforming protein RhoA, Rho cDNA clone 12, h12

Background: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015],

Gene Name: RHOA

Protein Name: Transforming protein RhoA

Molekulargewicht: 21 kDa

Gen-ID: 387

OMIM: 165390

UniProt: P61586

Pathways: Microtubule Dynamics, WNT Signalweg, Neurotrophin Signalübertragung, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, SARS-CoV-2 Protein Interaktom