Lamin A/C Antikörper (pSer22)
Kurzübersicht für Lamin A/C Antikörper (pSer22) (ABIN1532183)
Target
Alle Lamin A/C (LMNA) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 2-51, pSer22
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Spezifität
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Lamin A (Phospho-Ser22) Antibody detects endogenous levels of Lamin A only when phosphorylated at Ser22.
PhosphorylationH:S22 M:S22 R:S22
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Aufreinigung
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human Lamin A around the phosphorylation site of Ser22.
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500~1:1000 ELISA: 1:1000
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Kommentare
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Unigene-Number: Hs.594444 (NCBI Gene Symbol: LMNA)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable at -20°C for at least 1 year.
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Haltbarkeit
- 12 months
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: "Phenotypical Characterization of the Nuclear Egress of Recombinant Cytomegaloviruses Reveals Defective Replication upon ORF-UL50 Deletion but Not pUL50 Phosphosite Mutation." in: Viruses, Vol. 13, Issue 2, (2021) (PubMed).
: "Functional Relevance of the Interaction between Human Cyclins and the Cytomegalovirus-Encoded CDK-Like Protein Kinase pUL97." in: Viruses, Vol. 13, Issue 7, (2021) (PubMed).
: "The Complex Regulatory Role of Cytomegalovirus Nuclear Egress Protein pUL50 in the Production of Infectious Virus." in: Cells, Vol. 10, Issue 11, (2021) (PubMed).
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: "Phenotypical Characterization of the Nuclear Egress of Recombinant Cytomegaloviruses Reveals Defective Replication upon ORF-UL50 Deletion but Not pUL50 Phosphosite Mutation." in: Viruses, Vol. 13, Issue 2, (2021) (PubMed).
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- Lamin A/C (LMNA)
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Andere Bezeichnung
- Lamin A
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Hintergrund
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Synonyms: 70 kDa lamin, LAMA, LMN1, LMNA
NCBI Gene Symbol: LMNA
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Molekulargewicht
- 74 kDa
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Gen-ID
- 4000
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OMIM
- 115200
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UniProt
- P02545
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Pathways
- Apoptose, Caspase Kaskade in der Apoptose, ER-Nucleus Signaling, Protein targeting to Nucleus
Target
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