ITCH Antikörper (pTyr420)

Produktnummer ABIN1532110

Produktdetails anti-ITCH Antikörper

Target: ITCH (Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH))

Bindungsspezifität: AA 386-435, pTyr420

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ITCH Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Spezifität:

ITCH (Phospho-Tyr420) Antibody detects endogenous levels of ITCH only when phosphorylated at Tyr420.

PhosphorylationH:Y420 M:Y381

Aufreinigung: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ITCH around the phosphorylation site of Tyr420.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC: 1:50~1:100 ELISA: 1:20000

Kommentare:

Unigene-Number: Hs.632272 (NCBI Gene Symbol: ITCH)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable at -20°C for at least 1 year.

Haltbarkeit: 12 months

Details zu ITCH

Target: ITCH (Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH))

Andere Bezeichnung: ITCH (ITCH Produkte)

Hintergrund:

Synonyms: AIF4, AIP4, atrophin-1-interacting protein 4, Itchy homolog E3 ubiquitin protein ligase, NAPP1, NFE2-associated polypeptide 1, ubiquitin protein ligase ITCH

NCBI Gene Symbol: ITCH

Molekulargewicht: 102 kDa

Gen-ID: 83737

OMIM: 606409

UniProt: Q96J02

Pathways: Activation of Innate immune Response, CXCR4-mediated Signaling Events