c-FOS Antikörper (pSer32)

Produktnummer ABIN1532091

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch c-FOS in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für c-FOS Antikörper (pSer32) (ABIN1532091)

Target: c-FOS (c-Fos) (c-Fos)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser c-FOS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-c-FOS Antikörper

Bindungsspezifität: AA 15-64, pSer32

Verwendungszweck: c-Fos (phospho Ser32) Antibody

Spezifität: Phospho-c-Fos (S32) Polyclonal Antibody detects endogenous levels of c-Fos protein only when phosphorylated at S32.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human FOS around the phosphorylation site of Ser32. AA range:15-64

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu c-FOS

Target: c-FOS (c-Fos) (c-Fos)

Andere Bezeichnung: FOS

Hintergrund:

Synonyms: FOS, G0S7, Proto-oncogene c-Fos, Cellular oncogene fos, G0/G1 switch regulatory protein 7

Background: The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008],

Gene Name: FOS

Protein Name: Proto-oncogene c-Fos

Molekulargewicht: 40 kDa

Gen-ID: 2353

OMIM: 164810

UniProt: P01100

Pathways: S100 Proteine