HDAC8 Antikörper (pSer39)

Produktnummer ABIN1531858

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HDAC8 in WB, IHC, ELISA und IF. Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Maus.

Kurzübersicht für HDAC8 Antikörper (pSer39) (ABIN1531858)

Target: HDAC8 (Histone Deacetylase 8 (HDAC8))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HDAC8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-HDAC8 Antikörper

Bindungsspezifität: AA 5-54, pSer39

Verwendungszweck: HDAC8 (phospho Ser39) Antibody

Spezifität: Phospho-HDAC8 (S39) Polyclonal Antibody detects endogenous levels of HDAC8 protein only when phosphorylated at S39.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human HDAC8 around the phosphorylation site of Ser39. AA range:5-54

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu HDAC8

Target: HDAC8 (Histone Deacetylase 8 (HDAC8))

Andere Bezeichnung: HDAC8

Hintergrund:

Synonyms: HDAC8, HDACL1, CDA07, Histone deacetylase 8, HD8

Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA.The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009],

Gene Name: HDAC8

Protein Name: Histone deacetylase 8

Molekulargewicht: 41 kDa

Gen-ID: 55869

OMIM: 300269

UniProt: Q9BY41

Pathways: Cellular Glucan Metabolic Process