ERK1/2 Antikörper (pThr202)

Produktnummer ABIN1531831

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ERK1/2 in WB, IHC, IF und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für ERK1/2 Antikörper (pThr202) (ABIN1531831)

Target: ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERK1/2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Produktdetails anti-ERK1/2 Antikörper

Bindungsspezifität: AA 169-218, pThr202

Verwendungszweck: ERK 1/2 (phospho Thr202) Antibody

Spezifität: Phospho-ERK 1/2 (T202) Polyclonal Antibody detects endogenous levels of ERK 1/2 protein only when phosphorylated at T202.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human p44/42 MAP Kinase around the phosphorylation site of Thr202. AA range:169-218

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF 1:50-200 WB 1:500-2000, IHC 1:50-300 IHC 1:50-300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu ERK1/2

Target: ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))

Andere Bezeichnung: p44/42 MAP Kinase

Hintergrund:

Synonyms: MAPK3, ERK1, PRKM3, Mitogen-activated protein kinase 3, MAP kinase 3, MAPK 3, ERT2, Extracellular signal-regulated kinase 1, ERK-1, Insulin-stimulated MAP2 kinase, MAP kinase isoform p44, p44-MAPK, Microtubule-associated protein 2 kinase, p

Background: The protein encoded byThis gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008],

Gene Name: MAPK1/MAPK3

Protein Name: Mitogen-activated protein kinase 3

Molekulargewicht: 43 kDa

Gen-ID: 5595, 5594

OMIM: 601795

UniProt: P27361