Calmodulin 1 Antikörper (pSer81, pThr79)

Produktnummer ABIN1531529

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-Calmodulin 1 Antikörper wird verwendet zum Nachweis von Calmodulin 1 in Proben von Human, Ratte und Maus. Er wurde validiert für WB, ELISA, IHC und IF.

Kurzübersicht für Calmodulin 1 Antikörper (pSer81, pThr79) (ABIN1531529)

Target: Calmodulin 1 (CALM1)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Calmodulin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-Calmodulin 1 Antikörper

Bindungsspezifität: AA 46-95, pSer81, pThr79

Verwendungszweck: Calmodulin-1 (phospho Thr80/S82) Antibody

Spezifität: Phospho-Calmodulin (T80/S82) Polyclonal Antibody detects endogenous levels of Calmodulin protein only when phosphorylated at T80/S82.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Calmodulin-1 around the phosphorylation site of Thr79 and Ser81. AA range:46-95

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Referenzen für anti-Calmodulin 1 Antikörper (ABIN1531529)

Yokokura, Yurimoto, Matsuoka, Imataki, Dobashi, Bandoh, Matsunaga: "Calmodulin antagonists induce cell cycle arrest and apoptosis in vitro and inhibit tumor growth in vivo in human multiple myeloma." in: BMC cancer, Vol. 14, pp. 882, (2014) (PubMed).

Details zu Calmodulin 1

Target: Calmodulin 1 (CALM1)

Andere Bezeichnung: Calmodulin

Hintergrund:

Synonyms: CALM1, CALM, CAM, CAM1, CALM2, CAM2, CAMB, CALM3, CALML2, CAM3, CAMC, CAMIII, Calmodulin, CaM

Background: This gene encodes a member of the EF-hand calcium-binding protein family. It is one of three genes which encode an identical calcium binding protein which is one of the four subunits of phosphorylase kinase. Two pseudogenes have been identified on chromosome 7 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009],

Gene Name: CALM1

Protein Name: Calmodulin-1

Molekulargewicht: 16 kDa

Gen-ID: 801, 805, 808

OMIM: 114180

UniProt: P0DP23

Pathways: cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Phototransduction, BCR Signaling