BMX Antikörper (pTyr566)

Produktnummer ABIN1531499

Der Kaninchen Polyklonal anti-BMX Antikörper wird verwendet zum Nachweis von BMX in Proben von Human und Maus. Er wurde validiert für WB, IHC, ELISA und IF.

Kurzübersicht für BMX Antikörper (pTyr566) (ABIN1531499)

Target: BMX (BMX Non-Receptor Tyrosine Kinase (BMX))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BMX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-BMX Antikörper

Bindungsspezifität: AA 532-581, pTyr566

Verwendungszweck: Bmx (phospho Tyr566) Antibody

Spezifität: Phospho-Bmx (Y566) Polyclonal Antibody detects endogenous levels of Bmx protein only when phosphorylated at Y566.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ETK around the phosphorylation site of Tyr566. AA range:532-581

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu BMX

Target: BMX (BMX Non-Receptor Tyrosine Kinase (BMX))

Andere Bezeichnung: ETK

Hintergrund:

Synonyms: BMX, Cytoplasmic tyrosine-protein kinase BMX, Bone marrow tyrosine kinase gene in chromosome X protein, Epithelial and endothelial tyrosine kinase, ETK, NTK38

Background: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016],

Gene Name: BMX

Protein Name: Cytoplasmic tyrosine-protein kinase BMX

Molekulargewicht: 78 kDa

Gen-ID: 660

OMIM: 300101

UniProt: P51813