TK (AA 1-50), (pSer13) Antikörper

Produktnummer ABIN1531403

Der Kaninchen Polyklonal anti-TK Antikörper (ABIN1531403) detektiert spezifisch TK in ELISA, WB, IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte und Schwein.

Kurzübersicht für TK (AA 1-50), (pSer13) Antikörper (ABIN1531403)

Target: TK

Reaktivität: Human, Maus, Ratte, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails

Bindungsspezifität: AA 1-50, pSer13

Verwendungszweck: Thymidine Kinase (phospho Ser13) Antibody

Spezifität: Phospho-Thymidine Kinase (S13) Polyclonal Antibody detects endogenous levels of Thymidine Kinase protein only when phosphorylated at S13.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human TK around the phosphorylation site of Ser13. AA range:1-50

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Antigendetails

Target: TK

Hintergrund:

Synonyms: TK1, Thymidine kinase, cytosolic

Background: catalytic activity:ATP + thymidine = ADP + thymidine 5'-phosphate.,miscellaneous:Two forms have been identified in animal cells, one in cytosol and one in mitochondria. Activity of the cytosolic enzyme is high in proliferating cells and peaks during the S-phase of the cell cycle, it is very low in resting cells.,PTM:Phosphorylated on Ser-13 in mitosis.,similarity:Belongs to the thymidine kinase family.,

Gene Name: TK1

Protein Name: Thymidine kinase cytosolic

Molekulargewicht: 25 kDa

Gen-ID: 7083

OMIM: 188300

UniProt: P04183