IRS1 Antikörper (pSer323)
Kurzübersicht für IRS1 Antikörper (pSer323) (ABIN1531330)
Target
Alle IRS1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 289-338, pSer323
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Verwendungszweck
- IRS-1 (phospho Ser323) Antibody
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Spezifität
- Phospho-IRS-1 (S323) Polyclonal Antibody detects endogenous levels of IRS-1 protein only when phosphorylated at S323.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human IRS-1 around the phosphorylation site of Ser323. AA range:289-338
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- IRS1 (Insulin Receptor Substrate 1 (IRS1))
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Andere Bezeichnung
- IRS-1
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Hintergrund
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Synonyms: IRS1, Insulin receptor substrate 1, IRS-1
Background: This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. [provided by RefSeq, Nov 2009],
Gene Name: IRS1
Protein Name: Insulin receptor substrate 1
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Molekulargewicht
- 131 kDa
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Gen-ID
- 3667
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OMIM
- 125853
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UniProt
- P35568
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Pathways
- Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Negative Regulation of Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
Target
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