ITGB1 Antikörper (pThr788)
Kurzübersicht für ITGB1 Antikörper (pThr788) (ABIN1531289)
Target
Alle ITGB1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 749-798, pThr788
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Verwendungszweck
- Integrin β1 (phospho Thr788) Antibody
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Spezifität
- Phospho-Integrin β1 (T788) Polyclonal Antibody detects endogenous levels of Integrin β1 protein only when phosphorylated at T788.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human Integrin beta1 around the phosphorylation site of Thr788. AA range:749-798
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- ITGB1 (Integrin beta 1 (ITGB1))
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Andere Bezeichnung
- Integrin Beta1
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Hintergrund
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Synonyms: ITGB1, FNRB, MDF2, MSK12, Integrin beta-1, Fibronectin receptor subunit beta, VLA-4 subunit beta, CD antigen CD29
Background: Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells.This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Gene Name: ITGB1
Protein Name: Integrin beta-1
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Molekulargewicht
- 88 kDa
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Gen-ID
- 3688
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OMIM
- 135630
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UniProt
- P05556
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Pathways
- Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interaktom
Target
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