CD46 Antikörper (AA 40-320)

Produktnummer ABIN1512715

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CD46 in WB, IHC und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CD46 Antikörper (AA 40-320) (ABIN1512715)

Target: CD46

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD46 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-CD46 Antikörper

Bindungsspezifität: AA 40-320

Sequenz: TFEAMELIGK PKPYYEIGER VDYKCKKGYF YIPPLATHTI CDRNHTWLPV SDDACYRETC PYIRDPLNGQ AVPANGTYEF GYQMHFICNE GYYLIGEEIL YCELKGSVAI WSGKPPICEK VLCTPPPKIK NGKHTFSEVE VFEYLDAVTY SCDPAPGPDP FSLIGESTIY CGDNSVWSRA APECKVVKCR FPVVENGKQI SGFGKKFYYK ATVMFECDKG FYLDGSDTIV CDSNSTWDPP VPKCLKVSTS STTKSPASSA SGPRPTYKPP VSNYPGYPKP E

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 40-320 of human CD46 (NP_722548.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CD46

Target: CD46

Andere Bezeichnung: CD46

Hintergrund: The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.,AHUS2,MCP,MIC10,TLX,TRA2.10,CD46,Immunology & Inflammation,CD markers,Cell Intrinsic Innate Immunity Signaling Pathway,CD46

Molekulargewicht: 36 kDa/39 kDa/40 kDa/41 kDa/42 kDa/43 kDa/44 kDa

Gen-ID: 4179

UniProt: P15529

Pathways: Regulation of Actin Filament Polymerization