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CD73 Antikörper (FITC)

NT5E Reaktivität: Human FACS Wirt: Maus Monoclonal AD2 FITC

Produktnummer ABIN1504142

Datenblatt (PDF)

Target Alle CD73 (NT5E) Antikörper anzeigen

CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))
Reaktivität
122

74

31

18

18

16

4

2

1

1

1

1

1
Human
Wirt
91

43

22

2
Maus
Passende Sekundärantikörper
Klonalität
81

76

1
Monoklonal
Konjugat
65

14

12

9

8

5

4

4

3

3

3

3

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD73 Antikörper ist konjugiert mit FITC
Applikation
85

73

50

41

16

15

14

14

12

8

7

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1
Flow Cytometry (FACS)

Kreuzreaktivität (Details)

Species reactivity (tested):Human

Klon

AD2

Isotyp

IgG1

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Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Buffer

PBS, 15 mM sodium azide, 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA)

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Target

CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))

Andere Bezeichnung

CD73 (NT5E Produkte)

Hintergrund

CD73 (ecto-5´-nucleotidase) is a 70 kDa glycoprotein anchored to the extracellular leaflet of the plasma membrane by GPI. This ecto-enzyme catalyzes dephosphorylation of AMP to adenosine. CD73 is expressed in various types of cells, such as epithelial, muscle, and endothelial cells, neutrophils, lymphocytes and fibroblasts. Inflammatory mediators support CD73 expression and its enzymatic activity, leading to the release of adenosine, which modulates inflammation through adenosine receptors. CD73 is expressed in a variety of lymphomas and leukemias, including ALL and CLL, whereas immunodeficient patients usually express low levels of this protein.Synonyms: 5'-nucleotidase, NT5, NT5E, NTE

Pathways

Synaptic Membrane, Ribonucleoside Biosynthetic Process