POT1 Antikörper (AA 247-296)

Produktnummer ABIN1453800

Der Kaninchen Polyklonal anti-POT1 Antikörper (ABIN1453800) detektiert spezifisch POT1 in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Affe.

Kurzübersicht für POT1 Antikörper (AA 247-296) (ABIN1453800)

Target: POT1 (Protection of Telomeres 1 (POT1))

Reaktivität: Human, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-POT1 Antikörper

Bindungsspezifität: AA 247-296

Verwendungszweck: POT1 Antibody

Spezifität: POT1 Polyclonal Antibody detects endogenous levels of POT1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human POT1. AA range:247-296

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000,IHC 1:50-300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu POT1

Target: POT1 (Protection of Telomeres 1 (POT1))

Andere Bezeichnung: POT1

Hintergrund:

Synonyms: POT1, Protection of telomeres protein 1, hPot1, POT1-like telomere end-binding protein

Background: protection of telomeres 1(POT1) Homo sapiens This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008],

Gene Name: POT1

Protein Name: Protection of telomeres protein 1

Molekulargewicht: 71 kDa

Gen-ID: 25913

OMIM: 606478

UniProt: Q9NUX5

Pathways: Zellzyklus, Telomere Maintenance