PFKM Antikörper (AA 320-369)

Produktnummer ABIN1453764

Der Kaninchen Polyklonal anti-PFKM Antikörper (ABIN1453764) detektiert spezifisch PFKM in WB, IHC, ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für PFKM Antikörper (AA 320-369) (ABIN1453764)

Target: PFKM (phosphofructokinase, Muscle (PFKM))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PFKM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-PFKM Antikörper

Bindungsspezifität: AA 320-369

Verwendungszweck: PFKM Antibody

Spezifität: PFKM Polyclonal Antibody detects endogenous levels of PFKM protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human PFK-1. AA range:320-369

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu PFKM

Target: PFKM (phosphofructokinase, Muscle (PFKM))

Andere Bezeichnung: PFK-1

Hintergrund:

Synonyms: PFKM, PFKX, 6-phosphofructokinase, muscle type, Phosphofructo-1-kinase isozyme A, PFK-A, Phosphofructokinase-M, Phosphofructokinase 1, Phosphohexokinase

Background: Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type.This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.[provided by RefSeq, Nov 2009],

Gene Name: PFKM

Protein Name: 6-phosphofructokinase muscle type

Molekulargewicht: 85 kDa

Gen-ID: 5213

OMIM: 610681

UniProt: P08237

Pathways: Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Warburg Effekt