DEFa3 Antikörper (AA 3-52)

Produktnummer ABIN1453197

Der Kaninchen Polyklonal anti-DEFa3 Antikörper (ABIN1453197) detektiert spezifisch DEFa3 in IHC, ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für DEFa3 Antikörper (AA 3-52) (ABIN1453197)

Target: DEFa3 (Defensin, alpha 3, Neutrophil-Specific (DEFa3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DEFa3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-DEFa3 Antikörper

Bindungsspezifität: AA 3-52

Verwendungszweck: Defensin α3 Antibody

Spezifität: Defensin α3 Polyclonal Antibody detects endogenous levels of Defensin α3 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human Defensin alpha3. AA range:3-52

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu DEFa3

Target: DEFa3 (Defensin, alpha 3, Neutrophil-Specific (DEFa3))

Andere Bezeichnung: Defensin Alpha3

Hintergrund:

Synonyms: DEFA3, DEF3, Neutrophil defensin 3, Defensin, alpha 3, HNP-3, HP-3, HP3

Background: defensin alpha 3(DEFA3) Homo sapiens Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif.The protein encoded by this gene, defensin, alpha 3, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 1 by only one amino acid. This gene and the gene encoding defensin, alpha 1 are both subject to copy number variation. [provided by RefSeq, Oct 2014],

Gene Name: DEFA3

Protein Name: Neutrophil defensin 3

Molekulargewicht: 10 kDa

Gen-ID: 1668

OMIM: 604522

UniProt: P59666

Pathways: Cellular Response to Molecule of Bacterial Origin