alpha Defensin 1 Antikörper (AA 3-52)

Produktnummer ABIN1453194

Der Kaninchen Polyklonal anti-alpha Defensin 1 Antikörper (ABIN1453194) detektiert spezifisch alpha Defensin 1 in IHC, ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für alpha Defensin 1 Antikörper (AA 3-52) (ABIN1453194)

Target: alpha Defensin 1 (DEFA1) (Defensin, alpha 1 (DEFA1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser alpha Defensin 1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-alpha Defensin 1 Antikörper

Bindungsspezifität: AA 3-52

Verwendungszweck: Defensin α1 Antibody

Spezifität: Defensin α1 Polyclonal Antibody detects endogenous levels of Defensin α1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human Defensin alpha1. AA range:3-52

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu alpha Defensin 1

Target: alpha Defensin 1 (DEFA1) (Defensin, alpha 1 (DEFA1))

Andere Bezeichnung: Defensin Alpha1

Hintergrund:

Synonyms: DEFA1, DEF1, DEFA2, MRS, DEFA1B, Neutrophil defensin 1, Defensin, alpha 1, HNP-1, HP-1, HP1

Background: defensin alpha 1(DEFA1) Homo sapiens Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif.The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation. [provided by RefSeq, Oct 2014],

Gene Name: DEFA1

Protein Name: Neutrophil defensin 1

Molekulargewicht: 10 kDa

Gen-ID: 1667

OMIM: 125220

UniProt: P59665

Pathways: Cellular Response to Molecule of Bacterial Origin