alpha Defensin 1 Antikörper (AA 1-94)

Produktnummer ABIN6139522

Produktdetails anti-alpha Defensin 1 Antikörper

Target: alpha Defensin 1 (DEFA1) (Defensin, alpha 1 (DEFA1))

Bindungsspezifität: AA 1-94

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser alpha Defensin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: MRTLAILAAI LLVALQAQAE PLQARADEVA AAPEQIAADI PEVVVSLAWD ESLAPKHPGS RKNMACYCRI PACIAGERRY GTCIYQGRLW AFCC

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-94 of human DEFA1 (NP_004075.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:100

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu alpha Defensin 1

Target: alpha Defensin 1 (DEFA1) (Defensin, alpha 1 (DEFA1))

Andere Bezeichnung: DEFA1 (DEFA1 Produkte)

Synonyme: DEF1 antikoerper, DEFA2 antikoerper, HNP-1 antikoerper, HP-1 antikoerper, HP1 antikoerper, MRS antikoerper, Defcr antikoerper, Defcr1 antikoerper, DEFA1 antikoerper, Defa antikoerper, Def antikoerper, GB19392 antikoerper, defensin alpha 1 antikoerper, defensin, alpha 1 antikoerper, defensin alpha 5 antikoerper, alpha-defensin 1A antikoerper, defensin 1 antikoerper, neutrophil defensin 1 antikoerper, DEFA1 antikoerper, Defa1 antikoerper, Defa5 antikoerper, MNP1A antikoerper, Def1 antikoerper, LOC107973256 antikoerper

Hintergrund: Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation.,DEFA1,DEF1,DEFA2,HNP-1,HP-1,HP1,MRS,Immunology & Inflammation,DEFA1

Molekulargewicht: 10 kDa

Gen-ID: 1667

UniProt: P59665

Pathways: Cellular Response to Molecule of Bacterial Origin