GJB2 Antikörper (AA 45-94)

Produktnummer ABIN1453152

Der Kaninchen Polyklonal anti-GJB2 Antikörper (ABIN1453152) detektiert spezifisch GJB2 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für GJB2 Antikörper (AA 45-94) (ABIN1453152)

Target: GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GJB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-GJB2 Antikörper

Bindungsspezifität: AA 45-94

Verwendungszweck: Connexin-26 Antibody

Spezifität: Connexin-26 Polyclonal Antibody detects endogenous levels of Connexin-26 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human Connexin-26. AA range:45-94

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu GJB2

Target: GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))

Andere Bezeichnung: Connexin-26

Hintergrund:

Synonyms: GJB2, Gap junction beta-2 protein, Connexin-26, Cx26

Background: This gene encodes a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. The gap junction proteins, also known as connexins, purified from fractions of enriched gap junctions from different tissues differ. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene are responsible for as much as 50 % of pre-lingual, recessive deafness. [provided by RefSeq, Oct 2008],

Gene Name: GJB2

Protein Name: Gap junction beta-2 protein

Molekulargewicht: 26 kDa

Gen-ID: 2706

OMIM: 121011

UniProt: P29033

Pathways: Sensory Perception of Sound, Cell-Cell Junction Organization