APOE Antikörper (AA 37-86)
Kurzübersicht für APOE Antikörper (AA 37-86) (ABIN1452933)
Target
Alle APOE Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 37-86
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Verwendungszweck
- ApoE Antibody
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Spezifität
- ApoE Polyclonal Antibody detects endogenous levels of ApoE protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- The antiserum was produced against synthesized peptide derived from human ApoE. AA range:37-86
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- APOE (Apolipoprotein E (APOE))
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Andere Bezeichnung
- ApoE
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Hintergrund
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Synonyms: APOE, Apolipoprotein E, Apo-E
Background: The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jun 2016],
Gene Name: APOE
Protein Name: Apolipoprotein E
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Molekulargewicht
- 36 kDa
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Gen-ID
- 348
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OMIM
- 107741
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UniProt
- P02649
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Pathways
- Regulation of Cell Size, Lipid Metabolism
Target
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