Desmoglein 1 Antikörper (AA 161-210)

Produktnummer ABIN1452168

Der Kaninchen Polyklonal anti-Desmoglein 1 Antikörper (ABIN1452168) detektiert spezifisch Desmoglein 1 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für Desmoglein 1 Antikörper (AA 161-210) (ABIN1452168)

Target: Desmoglein 1 (DSG1)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Desmoglein 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Desmoglein 1 Antikörper

Bindungsspezifität: AA 161-210

Verwendungszweck: Dsg1 Antibody

Spezifität: Dsg1 Polyclonal Antibody detects endogenous levels of Dsg1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human DSG1. AA range:161-210

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu Desmoglein 1

Target: Desmoglein 1 (DSG1)

Andere Bezeichnung: DSG1

Hintergrund:

Synonyms: DSG1, CDHF4, Desmoglein-1, Cadherin family member 4, Desmosomal glycoprotein 1, DG1, DGI, Pemphigus foliaceus antigen

Background: This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. [provided by RefSeq, Feb 2015],

Gene Name: DSG1

Protein Name: Desmoglein-1

Molekulargewicht: 113 kDa

Gen-ID: 1828

OMIM: 125670

UniProt: Q02413

Pathways: Cell-Cell Junction Organization