MYO5A Antikörper (AA 1784-1833)

Produktnummer ABIN1451376

Der Kaninchen Polyklonal anti-MYO5A Antikörper (ABIN1451376) detektiert spezifisch MYO5A in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für MYO5A Antikörper (AA 1784-1833) (ABIN1451376)

Target: MYO5A (Myosin VA (MYO5A))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYO5A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-MYO5A Antikörper

Bindungsspezifität: AA 1784-1833

Verwendungszweck: Myosin VA Antibody

Spezifität: Myosin VA Polyclonal Antibody detects endogenous levels of Myosin VA protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human MYO5A. AA range:1784-1833

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000,IHC 1:50-300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu MYO5A

Target: MYO5A (Myosin VA (MYO5A))

Andere Bezeichnung: MYO5A

Hintergrund:

Synonyms: MYO5A, MYH12, Unconventional myosin-Va, Dilute myosin heavy chain, non-muscle, Myosin heavy chain 12, Myosin-12, Myoxin

Background: This gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation.The protein encoded by this gene is abundant in melanocytes and nerve cells. Mutations in this gene cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease, or Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined. [provided by RefSeq, Dec 2008],

Gene Name: MYO5A

Protein Name: Unconventional myosin-Va

Molekulargewicht: 215 kDa

Gen-ID: 4644

OMIM: 160777

UniProt: Q9Y4I1

Pathways: Hormone Transport, Peptide Hormone Metabolism