MASP2 Antikörper (AA 227-276)

Produktnummer ABIN1451319

Der Kaninchen Polyklonal anti-MASP2 Antikörper (ABIN1451319) detektiert spezifisch MASP2 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für MASP2 Antikörper (AA 227-276) (ABIN1451319)

Target: MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MASP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-MASP2 Antikörper

Bindungsspezifität: AA 227-276

Verwendungszweck: MASP-2 Antibody

Spezifität: MASP-2 Polyclonal Antibody detects endogenous levels of MASP-2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human MASP2. AA range:227-276

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu MASP2

Target: MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))

Andere Bezeichnung: MASP2

Hintergrund:

Synonyms: MASP2, Mannan-binding lectin serine protease 2, MBL-associated serine protease 2, Mannose-binding protein-associated serine protease 2, MASP-2

Background: mannan binding lectin serine peptidase 2(MASP2) Homo sapiens This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016],

Gene Name: MASP2

Protein Name: Mannan-binding lectin serine protease 2

Molekulargewicht: 75 kDa

Gen-ID: 10747

OMIM: 605102

UniProt: O00187

Pathways: Komplementsystem