RCAN1 Antikörper (AA 201-250)

Produktnummer ABIN1451085

Der Kaninchen Polyklonal anti-RCAN1 Antikörper (ABIN1451085) detektiert spezifisch RCAN1 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für RCAN1 Antikörper (AA 201-250) (ABIN1451085)

Target: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RCAN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-RCAN1 Antikörper

Bindungsspezifität: AA 201-250

Verwendungszweck: DSCR 1 Antibody

Spezifität: DSCR 1 Polyclonal Antibody detects endogenous levels of DSCR 1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human RCAN1. AA range:201-250

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu RCAN1

Target: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Andere Bezeichnung: RCAN1

Hintergrund:

Synonyms: RCAN1, ADAPT78, CSP1, DSC1, DSCR1, Calcipressin-1, Adapt78, Down syndrome critical region protein 1, Myocyte-enriched calcineurin-interacting protein 1, MCIP1, Regulator of calcineurin 1

Background: The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013],

Gene Name: RCAN1

Protein Name: Calcipressin-1

Molekulargewicht: 22 kDa

Gen-ID: 1827

OMIM: 602917

UniProt: P53805

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development