NXF1 Antikörper (AA 1-50)

Produktnummer ABIN1450884

Der Kaninchen Polyklonal anti-NXF1 Antikörper (ABIN1450884) detektiert spezifisch NXF1 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für NXF1 Antikörper (AA 1-50) (ABIN1450884)

Target: NXF1 (Nuclear RNA Export Factor 1 (NXF1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NXF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-NXF1 Antikörper

Bindungsspezifität: AA 1-50

Verwendungszweck: TAP Antibody

Spezifität: TAP Polyclonal Antibody detects endogenous levels of TAP protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human NXF1. AA range:1-50

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu NXF1

Target: NXF1 (Nuclear RNA Export Factor 1 (NXF1))

Andere Bezeichnung: NXF1

Hintergrund:

Synonyms: NXF1, TAP, Nuclear RNA export factor 1, Tip-associated protein, Tip-associating protein, mRNA export factor TAP

Background: This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results

Gene Name: NXF1

Protein Name: Nuclear RNA export factor 1

Molekulargewicht: 70 kDa

Gen-ID: 10482

OMIM: 602647

UniProt: Q9UBU9