PINX1 Antikörper (AA 121-170)
Kurzübersicht für PINX1 Antikörper (AA 121-170) (ABIN1450857)
Target
Alle PINX1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 121-170
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Verwendungszweck
- PinX1 Antibody
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Spezifität
- PinX1 Polyclonal Antibody detects endogenous levels of PinX1 protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human PINX1. AA range:121-170
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Isotyp
- IgG
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Applikationshinweise
- IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))
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Andere Bezeichnung
- PINX1
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Hintergrund
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Synonyms: PINX1, LPTL, LPTS, PIN2/TERF1-interacting telomerase inhibitor 1, Liver-related putative tumor suppressor, Pin2-interacting protein X1, Protein 67-11-3, TRF1-interacting protein 1
Background: domain:The TID (telomerase inhibiting domain) domain is sufficient to bind TERT and inhibit its activity.,function:Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor.,similarity:Belongs to the PINX1 family.,similarity:Contains 1 G-patch domain.,subcellular location:In nucleoli and at telomere speckles.,subunit:Binds to MCRS1, TERT and TERF1.,tissue specificity:Ubiquitous, expressed at low levels. Not detectable in a number of hepatocarcinoma cell lines.,
Gene Name: PINX1
Protein Name: PIN2/TERF1-interacting telomerase inhibitor 1
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Molekulargewicht
- 37 kDa
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Gen-ID
- 54984
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OMIM
- 606505
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UniProt
- Q96BK5
Target
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