CD33 Antikörper (Middle Region)

Produktnummer ABIN1450097

Der Kaninchen Polyklonal Anti-CD33-Antikörper wurde für WB und EIA validiert. Er ist geeignet, CD33 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für CD33 Antikörper (Middle Region) (ABIN1450097)

Target: CD33

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD33 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-CD33 Antikörper

Bindungsspezifität: Middle Region

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: CD33 antibody was raised against a 14 amino acid synthetic peptide near the center of human CD33.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: CD33 antibody can be used for detection of CD33 by Western blot at 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu CD33

Target: CD33

Andere Bezeichnung: CD33 / SIGLEC3

Hintergrund: CD33 is a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family that is highly expressed on myeloid progenitor cells. Assessment of CD33 expression is of great importance in the immunodiagnosis of acute leukemia, allowing distinction between myeloid and lymphoid origin, as CD33 is generally restricted to the myelomonocytic lineage. CD33 can associate with the protein-tyrosine phosphatases SHP-1 and SHP-2 and thus could modulate downstream signaling events associated with cell activation. Common variants of CD33 have been found to be associated with late-onset Alzheimer's disease.Synonyms: Myeloid cell surface antigen CD33, Sialic acid-binding Ig-like lectin 3, Siglec-3, gp67

Gen-ID: 945

NCBI Accession: NP_001763