UHRF1BP1 Antikörper (Middle Region)

Produktnummer ABIN1450049

Der Kaninchen Polyklonal Anti-UHRF1BP1-Antikörper wurde für WB, IF, IHC (p) und EIA validiert. Er ist geeignet, UHRF1BP1 in Proben von Human und Maus zu detektieren.

Kurzübersicht für UHRF1BP1 Antikörper (Middle Region) (ABIN1450049)

Target: UHRF1BP1 (UHRF1 Binding Protein 1 (UHRF1BP1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UHRF1BP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-UHRF1BP1 Antikörper

Bindungsspezifität: Middle Region

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid synthetic peptide near the center of Human UHRF1BP1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu UHRF1BP1

Target: UHRF1BP1 (UHRF1 Binding Protein 1 (UHRF1BP1))

Andere Bezeichnung: UHRF1BP1

Hintergrund: The Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1 (UHRF1BP1), also known as ICBP90, is a transcription and cell cycle regulator. It specifically binds to the histone H3 N-terminal tail when methylated on K9 by two functional domains, a PHD finger that defines the binding specificity and an SRA (SET- and RING-associated) domain that promotes binding activity. UHRF1BP1 is required for proper heterochromatin formation in mammalian cells. Furthermore, UHRF1BP1 is thought to be a pivotal target for the ERK1/2 signaling pathway to control the proliferation of Jurkat T cells.Synonyms: ICBP90-binding protein 1, UHRF1 binding protein 1, Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1

Gen-ID: 54887

NCBI Accession: NP_060224