WDR35 Antikörper (N-Term)

Produktnummer ABIN1449959

Produktdetails anti-WDR35 Antikörper

Target: WDR35 (WD Repeat Domain 35 (WDR35))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WDR35 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid synthetic peptide near the amino terminus of Human WDR35

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu WDR35

Target: WDR35 (WD Repeat Domain 35 (WDR35))

Andere Bezeichnung: WDR35 (WDR35 Produkte)

Synonyme: 4930459M12Rik antikoerper, 4931430C06 antikoerper, mKIAA1336 antikoerper, RGD1564116 antikoerper, Wdr35 antikoerper, CED2 antikoerper, IFT121 antikoerper, im:7159945 antikoerper, si:ch211-206k20.4 antikoerper, WD repeat domain 35 antikoerper, Wdr35 antikoerper, WDR35 antikoerper, wdr35 antikoerper

Hintergrund: WD40 repeats are a common structural module in eukaryotic proteins, and proteins containing WD40 domains have a wide range of functions, including signal transduction, cell cycle regulation, RNA splicing, and transcription. One such protein, WDR35, also known as CED2, has been shown to be mutated in patients with Sensenbrenner syndrome/cranioectodermal dysplasia (CED), an autosomal-recessive disease that is characterized by craniosynstosis and ectodermal and skeletal abnormalities. WDR35 localizes to cilia and dentrosomes during embryogenesis and human and mouse fibroblasts that lack this gene fail to produce cilia. Mutations in this gene can also cause short-rib polydactyly syndromes due to abnormal ciliogenesis.Synonyms: IFT121, Intraflagellar transport protein 121 homolog, KIAA1336, WD repeat-containing protein 35

Gen-ID: 57539

NCBI Accession: NP_001006658

Pathways: Hedgehog Signalweg