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WDR35 Antikörper (N-Term)

Der Rabbit Polyclonal Anti-WDR35-Antikörper wurde für IHC (p), EIA validiert. Er ist geeignet, WDR35 in Proben von Human zu detektieren.
Produktnummer ABIN1449959

Kurzübersicht für WDR35 Antikörper (N-Term) (ABIN1449959)

Target

Alle WDR35 Antikörper anzeigen
WDR35 (WD Repeat Domain 35 (WDR35))

Reaktivität

  • 9
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 9
Kaninchen

Klonalität

  • 9
Polyklonal

Konjugat

  • 6
  • 1
  • 1
  • 1
Dieser WDR35 Antikörper ist unkonjugiert

Applikation

  • 4
  • 4
  • 1
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 4
    • 3
    • 1
    • 1
    • 1
    N-Term

    Aufreinigung

    Affinity chromatography purified via peptide column

    Immunogen

    16 amino acid synthetic peptide near the amino terminus of Human WDR35

    Isotyp

    IgG
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1.0 mg/mL

    Buffer

    PBS containing 0.02 % Sodium Azide as preservative

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target

    WDR35 (WD Repeat Domain 35 (WDR35))

    Andere Bezeichnung

    WDR35

    Hintergrund

    WD40 repeats are a common structural module in eukaryotic proteins, and proteins containing WD40 domains have a wide range of functions, including signal transduction, cell cycle regulation, RNA splicing, and transcription. One such protein, WDR35, also known as CED2, has been shown to be mutated in patients with Sensenbrenner syndrome/cranioectodermal dysplasia (CED), an autosomal-recessive disease that is characterized by craniosynstosis and ectodermal and skeletal abnormalities. WDR35 localizes to cilia and dentrosomes during embryogenesis and human and mouse fibroblasts that lack this gene fail to produce cilia. Mutations in this gene can also cause short-rib polydactyly syndromes due to abnormal ciliogenesis.Synonyms: IFT121, Intraflagellar transport protein 121 homolog, KIAA1336, WD repeat-containing protein 35

    Gen-ID

    57539

    NCBI Accession

    NP_001006658

    Pathways

    Hedgehog Signalweg
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