KPNA7 Antikörper (N-Term)

Produktnummer ABIN1449957

Der Kaninchen Polyklonal anti-KPNA7 Antikörper (ABIN1449957) detektiert spezifisch KPNA7 in IHC (p) und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für KPNA7 Antikörper (N-Term) (ABIN1449957)

Target: KPNA7 (Karyopherin alpha 7 (Importin alpha 8) (KPNA7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KPNA7 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-KPNA7 Antikörper

Bindungsspezifität: N-Term

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 13 amino acid synthetic peptide near the amino terminus of Human KPNA7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu KPNA7

Target: KPNA7 (Karyopherin alpha 7 (Importin alpha 8) (KPNA7))

Andere Bezeichnung: KPNA7

Hintergrund: Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA7 is most closely related to KPNA2, but unlike KPNA2, KPNA7 primarily localizes to the nucleus. It has been suggested that KPNA7 may play a role in the transport of essential nuclear proteins required for early embryogenesis.Synonyms: Importin alpha 8, Importin subunit alpha-8, Karyopherin alpha 7, Karyopherin subunit alpha-7

Gen-ID: 402569

NCBI Accession: NP_001139187

Pathways: Protein targeting to Nucleus