KPNA7 Antikörper (N-Term)

Produktnummer ABIN6991419

Produktdetails anti-KPNA7 Antikörper

Target: KPNA7 (Karyopherin alpha 7 (Importin alpha 8) (KPNA7))

Bindungsspezifität: AA 40-90, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KPNA7 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: KPNA7 antibody is human specific. KPNA7 antibody is predicted to not cross-react with other Importin alpha family members.

Aufreinigung: KPNA7 Antibody is affinity chromatography purified via peptide column.

Immunogen: KPNA7 antibody was raised against a 13 amino acid synthetic peptide near the amino terminus of human KPNA7. The immunogen is located within amino acids 40 - 90 of KPNA7.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: KPNA7 antibody can be used for detection of KPNA7 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: KPNA7 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: KPNA7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu KPNA7

Target: KPNA7 (Karyopherin alpha 7 (Importin alpha 8) (KPNA7))

Andere Bezeichnung: KPNA7 (KPNA7 Produkte)

Synonyme: KPNA7 antikoerper, AW146299 antikoerper, Gm1055 antikoerper, karyopherin subunit alpha 7 antikoerper, karyopherin alpha 7 (importin alpha 8) antikoerper, KPNA7 antikoerper, kpna7 antikoerper, Kpna7 antikoerper

Hintergrund: KPNA7 Antibody: Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA7 is most closely related to KPNA2, but unlike KPNA2, KPNA7 primarily localizes to the nucleus. It has been suggested that KPNA7 may play a role in the transport of essential nuclear proteins required for early embryogenesis.

Gen-ID: 402569

NCBI Accession: NP_001139187

UniProt: A9QM74

Pathways: Protein targeting to Nucleus