PRC1 Antikörper (Middle Region)

Produktnummer ABIN1449936

Dieses Anti-PRC1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PRC1 in WB, IF, IHC (p) und EIA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für PRC1 Antikörper (Middle Region) (ABIN1449936)

Target: PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-PRC1 Antikörper

Bindungsspezifität: Middle Region

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse, Rat.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid synthetic peptide near the center of Human PRC1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PRC1

Target: PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))

Andere Bezeichnung: PRC1

Hintergrund: PRC1 (Protein Regulator of Cytokinesis 1) is a key regulator of cytokinesis and has been identified as a substrate for several cyclin-dependent kinases (CDKs). High levels of PRC1 expression occurs during S and G2/M and drops dramatically after mitosis exit and G1 entry. It is located in the nucleus during interphase and binds to the midzone of mitotic spindles during anaphase and is localized to the cell midbody during cytokinesis. Depletion of PRC1 has been shown to prevent cellular cleavage, but it has no effect on nuclear division, demonstrating the importance of PRC1 in mitosis.Synonyms: ASE1, Protein regulator of cytokinesis 1

Gen-ID: 9055

NCBI Accession: NP_003972